Oxidative Stress

Triphala ameliorates nephropathy via inhibition of TGF-β1 and oxidative stress.

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PMID: Pharmacology. 2020;105(11-12):681-691. Epub 2020 Jul 16. PMID: 32674108 Abstract Title: Triphala Ameliorates Nephropathy via Inhibition of TGF-β1 and Oxidative Stress in Diabetic Rats. Abstract: INTRODUCTION: Advanced glycation end products, oxidative stress, and TGF-β expression play a crucial role in the pathophysiology of diabetic nephropathy. Inhibition of oxidative stress and TGF-β expression by natural traditional … Read more

β-Patchoulene preconditioning protects mice against hepatic ischemia-reperfusion injury.

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PMID: J Surg Res. 2022 07;275:161-171. Epub 2022 Mar 10. PMID: 35279582 Abstract Title: β-Patchoulene Preconditioning Protects Mice Against Hepatic Ischemia-Reperfusion Injury by Regulating Nrf2/HO-1 Signaling Pathway. Abstract: INTRODUCTION: Hepatic ischemia-reperfusion (I/R) injury is one of the main causes of liver dysfunction after liver resection and transplantation. Hepatic I/R was characterized by the tissue hypoxia … Read more

Ameliorative potential role of Rosmarinus officinalis extract on toxicity induced by etoposide.

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PMID: Braz J Biol. 2022;84:e258234. Epub 2022 Jul 11. PMID: 35830129 Abstract Title: Ameliorative potential role of Rosmarinus officinalis extract on toxicity induced by etoposide in male albino rats. Abstract: The present work was shown to assess the effect of administration of rosemary extract on etoposide-induced toxicity, injury and proliferation in male rats were investigated. … Read more

These results suggested that panaxatriol saponin has therapeutic potential for myocardial ischemia-reperfusion injury by targeting Keap1 / Nrf2 activity.

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PMID: Oxid Med Cell Longev. 2022; 2022: 9626703. Epub 2022 May 27. PMID: 35669855 Abstract Title: Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1 / Nrf2 Activity. Abstract: Myocardial ischemia-reperfusion injury (MIRI) is a type of severe injury to the ischemic … Read more

These findings demonstrate that the protective effect of spirulina against ulcerative colitis.

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PMID: J Zhejiang Univ Sci B. 2022 Jun 15; 23 (6): 481-501. PMID: 35686527 Abstract Title: aqueous extracts ameliorate colonic mucosal damage and modulate gut microbiota disorder in mice with ulcerative colitis by inhibiting inflammation and oxidative stress. Abstract: Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease (IBD) that has become a … Read more

Echinacoside alleviates acetaminophen-induced liver injury.

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PMID: J Appl Biomed. 2021 05; 19 (2): 105-112. Epub 2021 Apr 26. PMID: 34907710 Abstract Title: Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice. Abstract: This study evaluates the protective effect of Echinacoside on acute liver toxicity induced by acetaminophen in mice and the mechanism behind it. Echinacoside … Read more

Hepatoprotective effects of astragaloside IV and formononetin against oxidative injury.

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PMID: FASEB J. 2022 May; 36 Suppl 1. PMID: 35554062 Abstract Title: Hepatoprotective Effects of Astragaloside IV and Formononetin Against Oxidative Injury. Abstract: The mitochondrial SIRT3 is a major deacetylase protein that regulates important mitochondrial biology, including metabolic pathways, reactive oxygen species detoxification, mitochondrial dynamics, and the mitochondrial unfolded protein response. We found that astragalus … Read more

Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice.

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PMID: Sci Total Environ. 2022 May 9: 155813. Epub 2022 May 9. PMID: 35550907 Abstract Title: Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice. Abstract: Increasing evidence shows that di-2-ethylhexyl phthalate (DEHP), mostly commonly used phthalate for the production of flexible polyvinyl chloride (PVC), has the potential to induce serious health risks … Read more

Butylphthalide could be a therapeutic potential against doxorubicin-induced neurotoxicity.

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PMID: Oxid Med Cell Longev. 2018; 2018: 9125601. Epub 2018 Aug 16. PMID: 30186550 Abstract Title: Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes. Abstract: Doxorubicin (DOX) is a broad-spectrum antitumor drug while its use is limited due to its neurobiological side effects associated with depression. We investigated … Read more

A comprehensive study to evaluate the wound healing potential of okra.

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PMID: J Ethnopharmacol. 2022 Apr 6; 287: 114843. Epub 2021 Nov 18. PMID: 34801610 Abstract Title: A comprehensive study to evaluate the wound healing potential of okra (Abelmoschus esculentus) fruit. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Okra fruit (Abelmoschus esculentus (L.) Moench) has been extensively used for the treatment of skin damage and subcutaneous tissue abscess for many … Read more