Interleukin-6 Downregulation

Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease.

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PMID: J Ethnopharmacol. 2022 Jun 28; 292: 115225. Epub 2022 Mar 25. PMID: 35341932 Abstract Title: Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease through regulating intestinal flora and inhibiting TAK1 / p38MAPK / p65NF-κB pathway. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: The therapeutic properties of Hippophae rhamnoides L. were already known … Read more

The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19.

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PMID: Phytomed Plus. 2021 Nov; 1 (4): 100058. Epub 2021 Mar 18. PMID: 35403084 Abstract Title: The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19. Abstract: Background: The corona virus disease 2019 (COVID-19) pandemic has highlighted the fact that there are few effective antiviral agents for treating severe … Read more

Diosgenin inhibits ER stress-induced inflammation in the aorta.

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PMID: Chem Biol Interact. 2022 May 1; 358: 109885. Epub 2022 Mar 16. PMID: 35305976 Abstract Title: Diosgenin inhibits ER stress-induced inflammation in the aorta via iRhom2 / TACE mediated signaling in experimental diabetic rats: An in vivo and in silico approach. Abstract: Hyperglycemia, hyperlipidemia, and atherosclerotic lesions may cause inflammation, which leads to chemokine … Read more

Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis.

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PMID: Phytomedicine. 2022 Feb 15; 99: 153991. Epub 2022 Feb 15. PMID: 35217435 Abstract Title: Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis. Abstract: BACKGROUND: It is a research hotspot to use natural compounds in treatment of cerebral ischemia reperfusion (I / R) for a refractory disease … Read more

Cannabinoids alleviate the lipopolysaccharide-induced cytokine storm.

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PMID: Cells. 2022 Apr 20; 11 (9). Epub 2022 Apr 20. PMID: 35563697 Abstract Title: Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro. Abstract: Cannabinoids, mainly cannabidiol (CBD) andΔ-tetrahydrocannabinol (THC), are the most studied group of compounds obtained from because of their several pharmaceutical properties. … Read more

Echinacoside alleviates acetaminophen-induced liver injury.

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PMID: J Appl Biomed. 2021 05; 19 (2): 105-112. Epub 2021 Apr 26. PMID: 34907710 Abstract Title: Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice. Abstract: This study evaluates the protective effect of Echinacoside on acute liver toxicity induced by acetaminophen in mice and the mechanism behind it. Echinacoside … Read more

Exploring the mechanism whereby sinensetin delays the progression of pulmonary fibrosis.

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PMID: Front Pharmacol. 2021; 12: 693061. Epub 2021 Jun 18. PMID: 34220517 Abstract Title: Exploring the Mechanism Whereby Sinensetin Delays the Progression of Pulmonary Fibrosis Based on Network Pharmacology and Pulmonary Fibrosis Models. Abstract: The incidence of pulmonary fibrosis (PF), a progressively fatal disease, has increased in recent years. However, there are no effective medicines … Read more

Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis L.

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PMID: BMC Complement Med Ther. 2022 May 12; 22 (1): 131. Epub 2022 May 12. PMID: 35550086 Abstract Title: Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis L. Abstract: BACKGROUND: Cognitive health is of great interest to society, with neuroinflammation and systemic inflammation age-related risk factors. that are linked to declines … Read more

Profile of insulin resistance in adipose tissue of diet induced obese mice in response to anti-obesity treatment.

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PMID: FASEB J. 2022 May; 36 Suppl 1. PMID: 35559539 Abstract Title: Profile of insulin resistance in adipose tissue of diet induced obese mice in response to anti-obesity treatment. Abstract: BACKGROUND: Adipose tissue is an insulin-responsive organ that contributes to both glucose and lipid metabolism. Insulin resistance (IR) is when insulin-dependent tissues lose their sensitivity … Read more

Topical application of total flavonoids of Hippophae rhamnoides improved atopic dermatitis-like lesions.

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PMID: J Ethnopharmacol. 2022 Mar 16; 292: 115195. Epub 2022 Mar 16. PMID: 35306042 Abstract Title: Total flavonoids of sea buckthorn (Hippophae rhamnoides L.) improve MC903-induced atopic dermatitis-like lesions. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Sea buckthorn (Hippophae rhamnoides L.) is popularly used as a herbal medicine and food additive in the world. Total flavonoids of Hippophae rhamnoides … Read more