Interleukin-1 beta downregulation

Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis.

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PMID: Phytomedicine. 2022 Feb 15; 99: 153991. Epub 2022 Feb 15. PMID: 35217435 Abstract Title: Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis. Abstract: BACKGROUND: It is a research hotspot to use natural compounds in treatment of cerebral ischemia reperfusion (I / R) for a refractory disease … Read more

Ginsenoside Rb1 alleviates bleomycin-induced pulmonary inflammation and fibrosis.

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PMID: Drug Des Devel Ther. 2022; 16: 1793-1809. Epub 2022 Jun 13. PMID: 35719213 Abstract Title: Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflamome Act Pathway. Abstract: Purpose: Idiopathic pulmonary fibrosis is a chronic and irreversible fibrotic interstitial pneumonia of unknown etiology … Read more

Echinacoside alleviates acetaminophen-induced liver injury.

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PMID: J Appl Biomed. 2021 05; 19 (2): 105-112. Epub 2021 Apr 26. PMID: 34907710 Abstract Title: Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice. Abstract: This study evaluates the protective effect of Echinacoside on acute liver toxicity induced by acetaminophen in mice and the mechanism behind it. Echinacoside … Read more

The protective effect of mangiferin on osteoarthritis.

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PMID: Physiol Res. 2022 03 25; 71 (1): 135-145. Epub 2022 Jan 19. PMID: 35043648 Abstract Title: The protective effect of mangiferin on osteoarthritis: An in vitro and in vivo study. Abstract: Mangiferin is a kind of polyphenol chemical compound separated from these herbal medicines of Mangifera indica L., Anemarrhena asphodeloides Bge. and Belamcanda chinensis … Read more

Topical application of total flavonoids of Hippophae rhamnoides improved atopic dermatitis-like lesions.

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PMID: J Ethnopharmacol. 2022 Mar 16; 292: 115195. Epub 2022 Mar 16. PMID: 35306042 Abstract Title: Total flavonoids of sea buckthorn (Hippophae rhamnoides L.) improve MC903-induced atopic dermatitis-like lesions. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Sea buckthorn (Hippophae rhamnoides L.) is popularly used as a herbal medicine and food additive in the world. Total flavonoids of Hippophae rhamnoides … Read more

Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy.

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PMID: Ann Transl Med. 2021 Dec; 9 (24): 1789. PMID: 35071483 Abstract Title: Ginsenoside Rg1 attenuates the inflammation and oxidative stress induced by diabetic nephropathy through regulating the PI3K / AKT / FOXO3 pathway. Abstract: Background: Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetes mellitus. Ginsenoside Rg1 (Rg1) is an … Read more