Diosgenin inhibits ER stress-induced inflammation in the aorta.

PMID: Chem Biol Interact. 2022 May 1; 358: 109885. Epub 2022 Mar 16. PMID: 35305976 Abstract Title: Diosgenin inhibits ER stress-induced inflammation in the aorta via iRhom2 / TACE mediated signaling in experimental diabetic rats: An in vivo and in silico approach. Abstract: Hyperglycemia, hyperlipidemia, and atherosclerotic lesions may cause inflammation, which leads to chemokine … Read more

Ginsenoside Rb1 inhibits astrocyte activation and promotes the transfer of astrocytic mitochondria to neurons against ischemic stroke.

PMID: Redox Biol. 2022 Jun 8; 54: 102363. Epub 2022 Jun 8. PMID: 35696763 Abstract Title: Ginsenoside Rb1 inhibits astrocyte activation and promotes the transfer of astrocytic mitochondria to neurons against ischemic stroke. Abstract: Astrocytes activation in response to stroke results in altered mitochondrial exchange with neurons. Ginsenoside Rb1is a major ginsenoside of Panax ginseng … Read more

Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis.

PMID: J Adv Res. 2022 Jun 16. Epub 2022 Jun 16. PMID: 35718080 Abstract Title: Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR / EST pathway. Abstract:: Intro duction Chronic psychological stress is a well-established risk factor for breast cancer development. Si-Ni-San (SNS) is … Read more

Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota.

PMID: BMC Cancer. 2022 May 20; 22 (1): 566. Epub 2022 May 20. PMID: 35596224 Abstract Title: Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota. Abstract: BACKGROUND: The role of Berberine (BBR) in colorectal cancer (CRC) and gut microbiota has begun to appreciate. However, there was no … Read more

Astragaloside IV inhibits the progression of liver cancer.

PMID: Am J Transl Res. 2022; 14 (3): 1551-1566. Epub 2022 Mar 15. PMID: 35422920 Abstract Title: Astragaloside IV inhibits the progression of liver cancer by modulating macrophage polarization through the TLR4 / NF-/B / STAT3 signaling pathway. Abstract: AIM: The purpose of the present research was to investigate the effect and mechanism of Astragaloside … Read more

Honokiol inhibits HIF-1α-mediated glycolysis to halt breast cancer growth.

PMID: Front Pharmacol. 2022; 13: 796763. Epub 2022 Mar 8. PMID: 35350760 Abstract Title: Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth. Abstract: Hypoxia-inducible factor-1α (HIF-1α) induces the expression of glycolysis-related genes, which plays a direct and key role in Warburg effect. In a recent study, honokiol (HNK) was identified as one of the … Read more

Ginsenoside Rg1 inhibits microglia pyroptosis induced by lipopolysaccharide.

PMID: J Inflamm Res. 2021; 14: 6619-6632. Epub 2021 Dec 7. PMID: 34908862 Abstract Title: Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling. Abstract: Purpose: Neuroinflammation runs through the whole process of nervous system diseases and brain injury. Inflammasomes are thought to be particularly relevant to immune homeostasis, and their dysregulation … Read more

Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p / KPNA4-dependent manner.

PMID: J Orthop Surg Res. 2021 Dec 20; 16 (1): 724. Epub 2021 Dec 20. PMID: 34930332 Abstract Title: Ginsenoside Rg3 inhibits osteosarcoma progression by reducing circ_0003074 expression in a miR-516b-5p / KPNA4-dependent manner. Abstract: BACKGROUND: Previous data have suggested that ginsenoside Rg3 (Rg3), isolated from the roots of Panax ginseng, plays a repressing role … Read more

Taxifolin inhibits 7,12-dimethylbenz (a) anthracene-induced breast carcinogenesis.

PMID: Pharmacogn Mag. 2018 Jan; 13 (Suppl 4): S749-S755. Epub 2018 Jan 31. PMID: 29491628 Abstract Title: Taxifolin Inhibits 7,12-Dimethylbenz (a) anthracene-induced Breast Carcinogenesis by Regulating AhR / CYP1A1 Signaling Pathway. Abstract: BACKGROUND: Breast cancer (BC), because of its invasive characteristics, is one of the most common and deadliest cancers among the female population around … Read more