Berberine retarded the growth of gastric cancer xenograft tumors.

PMID: World J Gastrointest Oncol. 2022 Apr 15; 14 (4): 842-857. PMID: 35582103 Abstract Title: Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α. Abstract: BACKGROUND: Gastric cancer is the third deadliest cancer in the world and ranks second in incidence and mortality of cancers in China. Despite advances … Read more

Screening of immune-related genes and predicting the immunotherapeutic effects of formononetin in breast cancer.

PMID: Evid Based Complement Alternat Med. 2022; 2022: 9942373. Epub 2022 Apr 15. PMID: 35463082 Abstract Title: Screening of Immune-Related Genes and Predicting the Immunotherapeutic Effects of Formononetin in Breast Cancer: A Bioinformatics Analysis. Abstract: Objective: Immunotherapy is a promising breast cancer treatment. Nonetheless, tumor heterogeneity and the interaction between immune cells in the tumor … Read more

Analgesic effect of electroacupuncture on bone cancer pain in rat model: the role of peripheral P2X3 receptor.

PMID: Purinergic Signal. 2022 Apr 28. Epub 2022 Apr 28. PMID: 35478452 Abstract Title: Analgesic effect of electroacupuncture on bone cancer pain in rat model: the role of peripheral P2X3 receptor. Abstract: Upregulation of P2X3 receptor (P2X3R) has been strongly implicated in nociceptive signaling including bone cancer pain (BCP). The present study, using rat bone … Read more

Astragaloside IV inhibits the progression of liver cancer.

PMID: Am J Transl Res. 2022; 14 (3): 1551-1566. Epub 2022 Mar 15. PMID: 35422920 Abstract Title: Astragaloside IV inhibits the progression of liver cancer by modulating macrophage polarization through the TLR4 / NF-/B / STAT3 signaling pathway. Abstract: AIM: The purpose of the present research was to investigate the effect and mechanism of Astragaloside … Read more

Honokiol inhibits HIF-1α-mediated glycolysis to halt breast cancer growth.

PMID: Front Pharmacol. 2022; 13: 796763. Epub 2022 Mar 8. PMID: 35350760 Abstract Title: Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth. Abstract: Hypoxia-inducible factor-1α (HIF-1α) induces the expression of glycolysis-related genes, which plays a direct and key role in Warburg effect. In a recent study, honokiol (HNK) was identified as one of the … Read more

The results of network pharmacology and experimental validation suggest that gingerol derivatives and compound gingerol can act against liver cancer.

PMID: J Pharm Pharmacol. 2022 Apr 16. Epub 2022 Apr 16. PMID: 35429380 Abstract Title: Prediction of the potential mechanism of compound gingerol against liver cancer based on network pharmacology and experimental verification. Abstract: OBJECTIVES: To explore gingerol’s potential mechanism for treating liver cancer using network pharmacology and molecular docking technology and to conduct in-vitro … Read more