Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.

PMID: Phytomedicine. 2022 May 27; 102: 154217. Epub 2022 May 27. PMID: 35660350 Abstract Title: Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora. Abstract: BACKGROUND: Colitis-associated cancer (CAC) is known to be a complex combination of tumor cells, non-tumor cells and a large intestinal flora. The increasing … Read more

Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota.

PMID: BMC Cancer. 2022 May 20; 22 (1): 566. Epub 2022 May 20. PMID: 35596224 Abstract Title: Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota. Abstract: BACKGROUND: The role of Berberine (BBR) in colorectal cancer (CRC) and gut microbiota has begun to appreciate. However, there was no … Read more

Berberine retarded the growth of gastric cancer xenograft tumors.

PMID: World J Gastrointest Oncol. 2022 Apr 15; 14 (4): 842-857. PMID: 35582103 Abstract Title: Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α. Abstract: BACKGROUND: Gastric cancer is the third deadliest cancer in the world and ranks second in incidence and mortality of cancers in China. Despite advances … Read more

Berberine alleviates NLRP3 inflammasome induced endothelial junction dysfunction.

PMID: Phytomedicine. 2022 Apr 26; 101: 154131. Epub 2022 Apr 26. PMID: 35533609 Abstract Title: Berberine alleviates NLRP3 inflammasome induced endothelial junction dysfunction through Casignalling in inflammatory vascular injury. Abstract: BACKGROUND: Berberine has received rising attention for its application in cardiovascular disease because of its relationship with inflammation. The endothelial NLRP3 inflammasome triggers inflammatory vascular … Read more