Effect of alpha-mangostin in the prevention of behavioral and neurochemical defects in methylmercury-induced neurotoxicity.

PMID: Toxicol Rep. 2022;9:977-998. Epub 2022 Apr 22. PMID: 35783250 Abstract Title: Effect of alpha-mangostin in the prevention of behavioral and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats. Abstract: Methylmercury (MeHg+) is a known neurotoxin that causes progressive motor neuron degeneration in the central nervous system. Axonal degeneration, oligodendrocyte degeneration, and myelin basic protein … Read more

Dl-3-n-butylphthalide alleviates behavioral and cognitive symptoms via modulating mitochondrial dynamics in the A53T-α-synuclein mouse model of Parkinson’s disease.

PMID: Front Neurosci. 2021; 15: 647266. Epub 2021 May 28. PMID: 34121985 Abstract Title: Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson’s Disease. Abstract: BACKGROUND: Aggregation and neurotoxicity of the presynaptic proteinα-synuclein and the progressive loss of nigral dopaminergic neurons are believed to be the key … Read more