Anti-Inflammatory Agents

Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy.

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PMID: BMC Complement Med Ther. 2022 Jan 20; 22 (1): 17. Epub 2022 Jan 20. PMID: 35057768 Abstract Title: Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages. Abstract: BACKGROUND: Diabetic nephropathy (DN) is one of the main causes of … Read more

These findings demonstrate that the protective effect of spirulina against ulcerative colitis.

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PMID: J Zhejiang Univ Sci B. 2022 Jun 15; 23 (6): 481-501. PMID: 35686527 Abstract Title: aqueous extracts ameliorate colonic mucosal damage and modulate gut microbiota disorder in mice with ulcerative colitis by inhibiting inflammation and oxidative stress. Abstract: Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease (IBD) that has become a … Read more

Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease.

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PMID: J Ethnopharmacol. 2022 Jun 28; 292: 115225. Epub 2022 Mar 25. PMID: 35341932 Abstract Title: Protective effect of flavonoids extract of Hippophae rhamnoides L. on alcoholic fatty liver disease through regulating intestinal flora and inhibiting TAK1 / p38MAPK / p65NF-κB pathway. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: The therapeutic properties of Hippophae rhamnoides L. were already known … Read more

Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD.

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PMID: Food Funct. 2022 Jun 21. Epub 2022 Jun 21. PMID: 35726797 Abstract Title: Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats. Abstract: Hepatic lipid accumulation, inflammation and gut microbiota dysbiosis are hallmarks of non-alcoholic fatty liver disease (NAFLD), which is the leading cause of … Read more

The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19.

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PMID: Phytomed Plus. 2021 Nov; 1 (4): 100058. Epub 2021 Mar 18. PMID: 35403084 Abstract Title: The potential of BEN815 as an anti-inflammatory, antiviral and antioxidant agent for the treatment of COVID-19. Abstract: Background: The corona virus disease 2019 (COVID-19) pandemic has highlighted the fact that there are few effective antiviral agents for treating severe … Read more

Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance.

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PMID: Burns Trauma. 2022; 10: tkac007. Epub 2022 Apr 9. PMID: 35415192 Abstract Title: Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance. Abstract: Background: Diabetes significantly delays wound healing through oxidative stress, inflammation and impaired re-epithelialization that lead to defective regulation of the healing process, although the related … Read more

Diosgenin prevents microglial activation and protects dopaminergic neurons from lipopolysaccharide-induced neural damage.

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PMID: Int J Mol Sci. 2021 Sep 26; 22 (19). Epub 2021 Sep 26. PMID: 34638697 Abstract Title: Diosgenin Prevents Microglial Activation and Protects Dopaminergic Neurons from Lipopolysaccharide-Induced Neural Damage In Vitro and In Vivo. Abstract: BACKGROUND: The prevention of age-related neurodegenerative disorders is an important issue in an aging society. Microglia-mediated neuroinflammation resulting in … Read more

Diosgenin inhibits ER stress-induced inflammation in the aorta.

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PMID: Chem Biol Interact. 2022 May 1; 358: 109885. Epub 2022 Mar 16. PMID: 35305976 Abstract Title: Diosgenin inhibits ER stress-induced inflammation in the aorta via iRhom2 / TACE mediated signaling in experimental diabetic rats: An in vivo and in silico approach. Abstract: Hyperglycemia, hyperlipidemia, and atherosclerotic lesions may cause inflammation, which leads to chemokine … Read more

Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis.

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PMID: Phytomedicine. 2022 Feb 15; 99: 153991. Epub 2022 Feb 15. PMID: 35217435 Abstract Title: Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI / HSP70 / NF-antiB anti-inflammatory axis. Abstract: BACKGROUND: It is a research hotspot to use natural compounds in treatment of cerebral ischemia reperfusion (I / R) for a refractory disease … Read more

Ginsenoside Rb1 alleviates bleomycin-induced pulmonary inflammation and fibrosis.

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PMID: Drug Des Devel Ther. 2022; 16: 1793-1809. Epub 2022 Jun 13. PMID: 35719213 Abstract Title: Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflamome Act Pathway. Abstract: Purpose: Idiopathic pulmonary fibrosis is a chronic and irreversible fibrotic interstitial pneumonia of unknown etiology … Read more