Alpha-mangostin alleviated HIF-1α-mediated angiogenesis in rats with adjuvant-induced arthritis.

PMID: Front Pharmacol. 2021 ;12:785586. Epub 2021 Dec 20. PMID: 34987400 Abstract Title: α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis. Abstract: A previously validated anti-rheumatic compound α-mangostin (MAN) shows significant metabolism regulatory effects. The current study aimed to clarify whether this property contributed to its inhibition on synovial angiogenesis. … Read more

Electroacupuncture treatment alleviated peripheral nerve injury-induced mechanical pain hypersensitivity.

PMID: Eur J Pain. 2022 May; 26 (5): 991-1005. Epub 2022 Feb 17. PMID: 35138669 Abstract Title: Electroacupuncture relieves neuropathic pain by inhibiting degradation of the ecto-nucleotidase PAP in the dorsal root ganglions of CCI mice. Abstract: BACKGROUND: Although electroacupuncture is widely used in chronic pain management, it is quite controversial due to its unclear … Read more

Bilobalide alleviated dextran sulfate sodium-induced experimental colitis.

PMID: Front Pharmacol. 2020; 11: 718. Epub 2020 May 21. PMID: 32670051 Abstract Title: Bilobalide Alleviated Dextran Sulfate Sodium-Induced Experimental Colitis by Inhibiting M1 Macrophage Polarization Through the NF-SignB Signaling Pathway. Abstract: Bilobalide, a unique substance has attracted significant interest as a novel therapeutic option for neuronal protection. However, there is a paucity of data … Read more