Betulinic acid improves cardiac-renal dysfunction caused by hypertrophy.

PMID: Nutrients. 2021 Sep 30; 13 (10). Epub 2021 Sep 30. PMID: 34684485 Abstract Title: Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling. Abstract: Cardiac hypertrophy can lead to congestive heart failure and is a leading cause of morbidity and mortality worldwide. In recent years, it has been essential to find the … Read more

Betulinic acid prevents liver fibrosis by binding Lck and suppressing Lck in HSC activation and proliferation.

PMID: J Ethnopharmacol. 2022 Jun 15; 296: 115459. Epub 2022 Jun 15. PMID: 35714879 Abstract Title: Betulinic acid prevents liver fibrosis by binding Lck and suppressing Lck in HSC activation and proliferation. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Hypericum japonicum Thunb. ex Murray (Hypericaceae), named ‘Tianjihuang’ is a traditional Chinese medicine with hepatoprotective, antibacterial, and antitumor effects. Betulinic … Read more

Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance.

PMID: Burns Trauma. 2022; 10: tkac007. Epub 2022 Apr 9. PMID: 35415192 Abstract Title: Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance. Abstract: Background: Diabetes significantly delays wound healing through oxidative stress, inflammation and impaired re-epithelialization that lead to defective regulation of the healing process, although the related … Read more

Echinacea angustifolia and Echinacea purpurea supplementation combined with vaginal hyaluronic acid to boost the remission of cervical low-grade squamous intraepithelial lesions.

PMID: Medicina (Kaunas). 2022 May 9; 58 (5). Epub 2022 May 9. PMID: 35630063 Abstract Title: andSupplementation Combined with Vaginal Hyaluronic Acid to Boost the Remission of Cervical Low-Grade Squamous Intraepithelial Lesions (L-SILs): A Randomized Controlled Trial. Abstract:: and purpurea have known immunomodulatory effects which boost viral clearance, including HPV infection. However, evidence regarding the … Read more

Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora.

PMID: Phytomedicine. 2022 May 27; 102: 154217. Epub 2022 May 27. PMID: 35660350 Abstract Title: Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora. Abstract: BACKGROUND: Colitis-associated cancer (CAC) is known to be a complex combination of tumor cells, non-tumor cells and a large intestinal flora. The increasing … Read more

Ganoderic acid A from Ganoderma lucidum protects against alcoholic liver injury.

PMID: Food Funct. 2022 May 23; 13 (10): 5820-5837. Epub 2022 May 23. PMID: 35543349 Abstract Title: Ganoderic acid A fromprotects against alcoholic liver injury through ameliorating the lipid metabolism and modulating the intestinal microbial composition. Abstract: Alcoholic liver injury is mainly caused by long-term excessive alcohol consumption and has become a global public threat … Read more

Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro insights.

PMID: RSC Adv. 2021 Sep 1; 11 (47): 29267-29286. Epub 2021 Sep 1. PMID: 35492070 Abstract Title: Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational andinsights. Abstract: Six compounds namely, tanshinone IIA (1), carnosic acid (2), rosmarinic acid (3), salvianolic acid B (4), baicalein (5), and … Read more

Ursolic acid as a potential inhibitor of Mycobacterium tuberculosis.

PMID: J Mol Model. 2022 Jan 13; 28 (2): 35. Epub 2022 Jan 13. PMID: 35022913 Abstract Title: Ursolic acid as a potential inhibitor of Mycobacterium tuberculosis cytochrome bc1 oxidase-a molecular modeling perspective. Abstract: The escalating burden of tuberculosis disease and drastic effects of current medicine has stimulated a search for alternative drugs. A medicinal … Read more

Ursolic acid ameliorates amyloid y-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome.

PMID: Neurotoxicology. 2022 01; 88: 231-240. Epub 2021 Dec 10. PMID: 34902447 Abstract Title: Ursolic acid ameliorates amyloidβ-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome. Abstract: BACKGROUND: Amyloidβ induces pathological symptoms in various neurodegenerative disorders. It is the hallmark of these neurodegenerative disorders, such as Alzheimer’s disease, and is reported to induce neurotoxicity … Read more

Neuroprotective effect of the standardised extract of Bacopa monnieri in a valproic acid model of autism spectrum disorder.

PMID: J Ethnopharmacol. 2022 Mar 26; 293: 115199. Epub 2022 Mar 26. PMID: 35346813 Abstract Title: Neuroprotective effect of the standardised extract of Bacopa monnieri (BacoMind) in valproic acid model of autism spectrum disorder in rats. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: Bacopa monnieri (BM) is commonly employed in the Indian traditional system of medicines, ie Ayurveda as … Read more